A passer-by called the emergency services and reported two men laying unconscious and bleeding heavily, shortly before 3.10am this morning.
Despite the efforts of paramedics and police, nothing could be done to save one of the men who died at the scene in Grove Lane, near to Holly Road in Handsworth.
The second was taken to hospital where he remains in a critical condition.
Both men are believed to be in their late 20s.
Claire Brown, a spokesperson for West Midlands Ambulance Service, said: “When ambulance staff arrived they found two patients who had sustained multiple serious injuries. One man was in traumatic cardiac arrest and was being given excellent CPR by police officers on scene.
“Ambulance staff and medics quickly took over resuscitation attempts and performed advanced life support on the man. Sadly nothing could be done to save him and he was confirmed dead at the scene.
“The condition of the second patient, a man in his 20s, quickly deteriorated and he too went into cardiac arrest. The medical team commenced advanced life support and after several minutes managed to restart the man’s heart. He was quickly transferred to hospital on blue lights.
“Medics at hospital were pre alerted to the arrival of the man who was said to be in a critical condition.”
West Midlands Police have now launched a murder investigation into the stabbing.
Detective Inspector Jim Munro, from West Midlands Police’s Force CID, said: “This is a tragedy for the family and friends of those concerned. They have our sincere sympathies.
“I would like to reassure both them and people living in the area that we are doing everything we can to find the person or people responsible.
“Extensive house to house enquiries will be taking place and we are already starting to identify CCTV cameras which may have captured the stabbings.
“A finger-tip search of the area will be conducted later today by a specialist police team while forensic scene investigators are set to conduct a detailed examination of the evidence so far.”
Grove Lane is closed from the junction of Soho Road to Douglas Road. Drivers and pedestrians are advised to avoid the area to prevent disruption to their journeys. Diversions are in place.